Mark Wang, M.D., PhD

Mark Wang, M.D., PhD
Dr. Wang is an Assistant Professor at Jefferson Medical College and has a special focus on the treatment of Hand and Wrist disorders. Raised in Bryn Mawr, PA, he is a Radnor High School alumnus. After graduating from Cornell University with a degree in Mechanical Engineering, he was selected to the MD, PhD Program at Thomas Jefferson University.

 He completed orthopedic residency training at the University of California, San Diego (Level 1 Trauma Center) prior to being awarded a fellowship in Hand and Upper Extremity Surgery at Thomas Jefferson University.  Upon completing his fellowship, he returned home to the greater Philadelphia area to serve the community that he grew up in.  He is the recipient of clinical and scientific awards, authoring several peer reviewed articles.

 
Education
  • B.S., Cornell University
  • M.D., Thomas Jefferson University
  • Ph.D., Thomas Jefferson University
  • Internship, General Surgery, University of California, San Diego
  • Residency, Orthopaedic Surgery, University of California, San Diego
  • Fellowship, Orthopaedic Hand Surgery, The Philadelphia Hand Center
Titles & Certifications
  • Board Certified, Orthopaedic Surgery
  • American Association for Hand Surgery (AAHS)
  • American Society for Surgery of the Hand (ASSH)
  • American Medical Association (AMA)
  • American Academy of Orthopaedic Surgeons (AAOS)
  • American Society of Cell Biology (ASCB)
  • Orthopaedic Research Society (ORS)
  • Certificate of Added Qualification in Hand Surgery
Hospital Affiliations
  • Bryn Mawr Hospital
  • Paoli Hospital
  • Riddle Surgery Center
  • Riverview Surgery Center
Highlights & Achievements
  • Eastern Orthopaedic Association Travel Grant, Outstanding Scientific Contribution, 42nd Annual Meeting, Eastern Orthopaedic Association, Williamsburg, VA
  • James B. Peake Award, Outstanding Clinical Service to U.S. Veterans, Department of Veterans Affairs, San Diego, CA
  • AOA-OREF Resident Leadership Forum, 7th Annual Meeting, The American Orthopaedic Association and Orthopaedic Research and Education Foundation, Bonita Springs, FL
  • Best Paper, Resident Research Day 2006, Combined Meeting UCSD and Naval Medical Center of San Diego, San Diego, CA
  • Dubbs Scholar Award, Thomas Jefferson University
  • Alumni Travel Fellowship Award, Thomas Jefferson University
  • Intramural Research Training Award, National Institutes of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health

 

PUBLICATIONS
 

1.     Steplewski, A., Fertala, J., Wang, M. L., Beredjiklian, P.K., Fertala, A. Matrix-Specific Anchors: A
        New Concept for Targeted Delivery and Retention of Therapeutic Cells.  Tissue Engineering, Part
        A (accepted).   
 
2.    Wang, M. L., Vosbikian, M. M., Abboudi, J., Beredjiklian, P. K.  (2014) Treatment of a Chronic    
      Multidrug-Resistant Cutaneous Mycobacterium chelonae Infection of the Hand with Wide Debridement
       and Skin-GraftingJBJS Case Connect 4(4):e102.

3.       Wang, M. L., Bednar, J.M.  (2012) Lunatocapitate and TriquetrohamateArthrodeses for

      Degenerative Arthritis of the Wrist.J Hand Surg Am 37(6):1136-41.
 

 

 

4.       Wang, M. L., Ballard, B. L., Kulidjian, A. A., Abrams, R. A.  (2011) Upper Extremity Reconstruction with a

      Humeral Endoprosthesis: A Novel Salvage Procedure following Multiple Revisions of Total Shoulder and Elbow Replacements. 

      J Shoulder and Elbow Surg20 (1) e1-8.

 

5.       Tran, W., Foran, J. R., Wang, M. L., Schwartz, A. K. (2008) Post-Surgical Bleeding Following the Treatment of A Chronic

      Morel-Lavalee Lesion: A Case Report and Literature Review. Orthopedics (8): 814.

 

6.       Wang, M. L., Massie, J., Allen, R. T., Lee, Y-P., Kim, C. W. (2008) Altered bioreactivity and limited osteoconductivity of

      calcium sulfate-based bone cements in the osteoporotic rat spine.Spine J 8 (2): 340-350.

 

7.       Vecchio, K. S., Zhang, X., Massie, J., Wang, M. L., Kim, C. W.  (2007) Conversion of Sea Urchin Spines to Mg-substituted

      Tricalcium Phosphate for Bone Implants.ActaBiomaterialia 3: 785-793.

 

8.       Vecchio, K. S., Zhang, X., Massie, J., Wang, M. L., Kim, C. W.  (2007) Conversion of Bulk Seashells to Biocompatible

      Hydroxyapatite for Bone Implants.ActaBiomaterialia 3: 910-918.

 

9.       Wang, M.L., Massie, J., Perry, A., Garfin, S. R., Kim, C.W. (2006): A Rat Osteoporotic Spine Model for the Evaluation of

      Bioresorbable Bone Cements.Spine J 6: 156S.

 

10.       Wang M. L., Sharkey P. F., Tuan R. S. (2004): Particle bioreactivity and wear-mediated osteolysis.J Arthroplasty 19:1028-38.

 

11.       Wang, M. L., Tuli, R., Manner, P. A., Sharkey, P. F., Hall, D. J. and Tuan, R. S. (2003). Direct and indirect induction of apoptosis in human mesenchymal stem cells in response to titanium particles. J Orthop Res 21(4): 697-707.

 

12.   Wang, M. L., Hauschka, P. V., Tuan, R. S. and Steinbeck, M. J. (2002). Exposure to particles stimulates superoxide production by human THP-1 macrophages and avian HD-11EM osteoclasts activated by tumor necrosis factor-alpha and PMA.

      J Arthroplasty 17(3): 335-46.

 

13.   Wang, M. L., Nesti, L. J., Tuli, R., Lazatin, J., Danielson, K. G., Sharkey, P. F. and Tuan, R. S. (2002). Titanium particles suppress expression of osteoblastic phenotype in human mesenchymal stem cells.J Orthop Res 20(6): 1175-84.

 

14.   Tuli, R., Seghatoleslami, M. R., Tuli, S., Wang, M. L., Hozack, W. J., Manner, P. A., Danielson, K. G. and Tuan, R. S. (2003).

      A simple, high-yield method for obtaining multipotentialmesenchymal progenitor cells from trabecular bone.

      MolBiotechnol 23(1): 37-49.

 

15.   Tuli, R., Tuli, S., Nandi, S., Wang, M. L., Alexander, P. G., Haleem-Smith, H., Hozack, W. J., Manner, P. A., Danielson, K. G.,

      Tuan, R. S. (2003).  Characterization of multipotentialmesenchymal progenitor cells derived from human trabecular bone.

      Stem Cells 21(6): 681-93.

 

16.   Nesti, L. J., Caterson, E. J., Wang, M. L., Chang, R., Chapovsky, F., Hoek, J. B. and Tuan, R. S. (2002). TGF-beta1 calcium

      signaling increases alpha5 integrin expression in osteoblasts.J Orthop Res 20(5): 1042-9.

 

17.   Nesti, L. J., Caterson, E. J., Wang, M. L., Chang, R., Chapovsky, F., Hoek, J. B. and Tuan, R. S. (2002). TGF-beta1-stimulated osteoblasts require intracellular calcium signaling for enhanced alpha5 integrin expression.Ann N Y AcadSci 961: 178-82.

 

PRESENTATIONS

1.       Wang, M.L.  (2012) Osteoporosis and Upper Extremity Fracture Management. Main Line Health, Bryn Mawr Hospital: Primarily Orthopaedics SymposiumBryn Mawr, PA.

 

2.       Wang, M.L.  (2012) Common Upper Extremity Disorders. Main Line Health, Bryn Mawr Hospital: Primarily Orthopaedics SymposiumBryn Mawr, PA.

 

3.       Wang, M.L.  (2012) Adult Bone Health and Osteoporosis. Main Line Health, Newtown Square Medical Center: Educational Lecture SeriesNewtown Square, PA.

 

4.      Wang, M.L.  (2011) Osteoporosis Management.  Chinese Cultural Association of Greater Philadelphia, Educational Lecture SeriesWayne, PA

 

5.      Wang, M. L., Bednar, J.M.  (2011) CLX Intercarpal Arthrodesis for the Treatment of the SLAC Wrist.  42nd Annual Meeting of the Eastern OrthopaedicSociety  (EOA), Williamsburg, VA.

 

6.      Wang, M. L., Bednar, J.M.  (2011) Limited Intercarpal Arthrodesis:  A Novel Motion Preserving Strategy for Degenerative Arthritis of the Wrist.  29th Annual Adrian D Flatt Residents and Fellows Conference in Hand Surgery at the 66th Annual Meeting of the American Society for Surgery of the Hand (ASSH), Las Vegas, NV.

 

7.      Wang, M. L., Bednar, J.M.  (2011) CLX Fusion:  A Novel Motion Preserving Strategy for Degenerative Arthritis of the Wrist.  13th Annual Lawrence H Schneider (LHS) Lectureship in Hand Surgery Residents and Fellows Paper Competition of the Philadelphia Hand Society and Hand Rehabilitation Foundation, Philadelphia, PA.

 

8.      Wang, M. L., Massie, J., Garfin, S. R., Kim, C. W.  (2006) 2006 Best Paper:An Investigation of Bioresorbable Bone Cements for the Local Treatment of Osteoporosis.Naval Medical Center of San Diego and University of California, San Diego Combined Resident Research Day 2006, San Diego, CA.

 

9.     Wang, M. L., Massie, J., Perry, A., Lu, L., Yaszemski, M., Garfin, S. R., Kim, C. W.  (2006) A Rat Osteoporotic Model For the Evaluation of Bioresorbable Bone Cements.The Combined Annual Meetings of the American Spinal Injury Association and the International Spinal Cord Society, Boston, MA.

 

10.   Wang, M. L., Tuli, R., Manner, P. A., Sharkey, P. F., Hall, D. J. and Tuan, R. S. (2003). Direct and Indirect induction of apoptosis in human mesenchymal stem cells in response to titanium particles.49th Annual Meeting of the Orthopaedic Research Society, New Orleans, LA.
 

 
 

 

POSTER PRESENTATIONS

1.      Wang, M. L., Massie, J., Lee, Y-P, Garfin, S. R., Kim, C. W.  (2007) Accelerated Bioresoption and Altered Osteoconductivity of Calcium Sulfate Based Bone Cements in the Rat Osteoporotic Spine.  53rd Annual Meeting of the Orthopaedic Research Society, San Diego, CA.

 

2.       Wang, M. L., Massie, J., Perry, A., Lu, L., Yaszemski, M., Garfin, S. R., Kim, C. W.  (2006) A Rat Osteoporotic Spine Model for the Evaluation of Bioresorbable Bone Cements.21st Annual Meeting of the North American Spine Society (NASS), Seattle, WA.

 

3.        Wang, M. L., Tuli, R., Manner, P. A., Sharkey, P. F., Hall, D. J. and Tuan, R. S. (2003). Direct and indirect induction of apoptosis in human mesenchymal stem cells in response to titanium particles. 42nd Annual Meeting of the American Society of Cell Biology, San Francisco, CA.

 

4.        Wang, M. L., Tuli, R., Manner, P. A., Sharkey, P. F., Hall, D. J. and Tuan, R. S. (2002). Direct and indirect induction of apoptosis in human mesenchymal stem cells in response to titanium particles.IRP Scientific Retreat, National Institute of Arthritis, and Musculoskeletal and Skin Diseases, Warrenton, VA.

 

5.        Wang, M. L., Nesti, L. J., Tuli, R., Lazatin, J., Danielson, K. G., Sharkey, P. F. and Tuan, R. S. (2002). Titanium particles suppress expression of osteoblastic phenotype in human mesenchymal stem cells.48th Annual Meeting of the Orthopaedic Research Society, Dallas, TX.

 

6.        Wang, M. L., Hauschka, P. V., Tuan, R. S. and Steinbeck, M. J. (2001). Exposure to particles stimulates superoxide production by human THP-1 macrophages and avian HD-11EM osteoclasts activated by tumor necrosis factor-alpha and PMA.Sigma Xi Scientific Research Society, Thomas Jefferson University, Philadelphia, PA.

 

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